Paulo Dybala scored twice as Juventus took charge of their Champions League quarter-final tie with Barcelona courtesy of a commanding home-leg display in Turin.
The Argentine forward curled home both of his goals before the break, the first from an angle inside the box and the second from a central position on the edge.
Juve turned a dominant lead into one that should see them go on and win the tie when Giorgio Chiellini showed strength and guile to steer home a header from a corner.
For the second European round running, Barca – who were as defensively suspect as they were in losing 4-0 to Paris St-Germain in the first leg of their last-16 tie – must come back from a heavy away defeat to progress.
However, after their record-breaking achievement to overturn that deficit against PSG, they will retain hope heading into the return leg at the Nou Camp on 19 April.